Survivor and Dihydromyricetin (DHM)

Dihydromyricetin is one of the main ingredients in Survivor’s unique formulation. Also known as Ampelopsin, Dihydromyricetin or DHM, it is a potent flavonoid which may help accelerate your body’s ability to break down acetaldehyde, the toxic product of alcohol metabolisation.

Studies suggest Dihydromyricetin (DHM) relieves alcohol (EtOH) toxicity and prevents intoxication by curtailing the absorption of alcohol in the gastrointestinal tract and promoting alcohol metabolisation in the liver – it has even been proposed as a ‘novel anti-intoxication medication’, which serves as evidence of its potential. Recently, there has been considerable academic interest in this flavonoid, as promising data on an entire swathe of benefits is emerging.

‘Dihydromyricetin (DHM) exhibits health-benefiting activities with minimum adverse effects. Dihydromyricetin (DHM) has been demonstrated to show antioxidative, anti-inflammatory, anticancer, antimicrobial, cell death-mediating, and lipid and glucose metabolism-regulatory activities.’

What is Dihydromyricetin (DHM)?

Long before Dihydromyricetin (DHM) was isolated and used as a supplement, everything began with the plants Hovenia Dulcis and Ampelopsis grossedentata - also known as the Japanese raisin tree and the Vine tree, respectively. These plants have been used as remedies against hangovers for centuries and consumed as teas, powder preparations, and infusions - and lately as capsules and pills. More recently western medicine has investigated these traditional remedies, with a view to identifying their active ingredients.

Originally known as Ampelopsin, Dihydromyricetin (DHM) is the major active compound in the extract of these plants. It was isolated from an extract of the fruit of Hovenia Dulcis by Hase et al. (1997). Later, it was also found in the fruit-stalk of the plant (Park et al., 2015).

Dihydromyricetin (or DHM for short) is assigned the CAS number 27200-12-0 by the Chemical Absctracts Service and has the chemical formula; (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one

Dihydromyricetin (DHM) belongs to a group of chemicals present in many types of plants called flavonoids - the name Ampelopsin is in recognition of once such source of flavonoids - Ampelopsis grossedentata. Flavonoids are associated with many health benefits, such as anti-inflammation, anti-carcinogenesis, anti-hepatotoxicity, relieving constipation, inhibition of lipid accumulation and many more (Panche et al. 2016).

In addition to DHM, Survivor contains a complementary blend of additional nutrients focussed on supporting your body in its response to alcohol consumption. We’ve included ingredients with a view to improving your quality of sleep, protecting against oxidative stress (which also leads to inflammation in the body), helping your body maintain normal cognitive function and normal energy yielding metabolism – as well as replenishing your reserves of various vitamins and minerals which can be depleted when consuming alcohol.
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